Bioterrorism, Glanders and melioidosis

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منابع مشابه

Bichat guidelines for the clinical management of glanders and melioidosis and bioterrorism-related glanders and melioidosis.

Glanders and melioidosis are two infectious diseases that are caused by Burkholderia mallei and Burkholderia pseudomallei respectively. Infection may be acquired through direct skin contact with contaminated soil or water. Ingestion of such contaminated water or dust is another way of contamination. Glanders and melioidosis have both been studied for weaponisation in several countries in the pa...

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Recent Progress in Melioidosis and Glanders

B. pseudomallei and B. mallei can survive hostile conditions, becoming resilient to many antimicrobial agents, including antibiotics. In the paper by Rholl et al. (2011), the resistance to β-lactams, such as ceftazidime, was investigated. Genetic analysis of penA gene, encoding a putative twin arginine translocase (TAT)-secreted β-lactamase, demonstrated that PenA is secreted via the TAT system...

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Burkholderia pseudomallei and Burkholderia mallei: Melioidosis and Glanders

The genus Burkholderia is currently composed of many species, but only three are notable pathogens for humans or animals: the former cepacia complex (described in Chapter 220) pseudomallei (the agent of melioidosis), and mallei (the agent of equine glanders). All three are aerobic, nonsporulating, straight or slightly curved gram-negative bacilli that were formerly placed in the genus Pseudomonas.

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Clinical Features and Laboratory Diagnosis of Infection with the Potential Bioterrorism Agents Burkholderia Mallei and Burkholderia Pseudomallei

Burkholderia mallei and Burkholderia pseudomallei are the causative organisms of Glanders and Melioidosis, respectively. Although now rare in Western countries, both organisms have recently gained much interest because of their unique potential as bioterrorism agents. These organisms are less familiar to medical and laboratory personnel than other select bioterrorism bacterial agents and thus h...

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Development of capsular polysaccharide-based glycoconjugates for immunization against melioidosis and glanders

Burkholderia pseudomallei and Burkholderia mallei, the etiologic agents of melioidosis and glanders, respectively, cause severe disease in humans and animals and are considered potential agents of biological warfare and terrorism. Diagnosis and treatment of infections caused by these pathogens can be challenging and, in the absence of chemotherapeutic intervention, acute disease is frequently f...

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ژورنال

عنوان ژورنال: Eurosurveillance

سال: 2005

ISSN: 1560-7917

DOI: 10.2807/esm.10.03.00528-en